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American Journal of Clinical Nutrition, Vol 8, 462-470, Copyright © 1960 by The American Society for Clinical Nutrition, Inc.

Nutritional Influences on the Metabolism of Bile Acids

OSCAR W. PORTMAN M.D.1

1 From the Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts

A number of experiments which indicated that dietary factors can influence the biliary and fecal excretion of bile acids are presented. These studies indicate that the effects observed may be related to variations in the way in which bile acids are chemically changed in the cecum by intestinal microorganisms and to the rate at which unmodified and modified bile acids are reabsorbed. Rats fed diets which tend to promote excretion of greater quantities of bile acids appear also to have lower serum cholesterol levels.






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Copyright © 1960 by The American Society for Nutrition