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American Journal of Clinical Nutrition, Vol 8, 547-561, Copyright © 1960 by The American Society for Clinical Nutrition, Inc.

The Hypothalamic Control of Gastric Hunger Contractions as a Component of the Mechanism of Regulation of Food Intake

JEAN MAYER PH.D., D.SC.1

1 From the Department of Nutrition, Harvard University School of Public Health, Boston, Massachusetts

Modern behavioral methods make it possible to study gastric contractions in relation to hunger behavior in animals as well as in man. It can thus be shown that the significance of these contractions is probably the same in the rat as it is in man.

Gastric hunger contractions appear to be, at least in part, under hypothalamic control. One of the areas involved is the ventromedial area which has been shown to be sensitive to the metabolic state of the individual. One of the factors in this control may be the rate of glucose utilization by the ventromedial area of the hypothalamus.




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