| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
VITAMIN D AND HEALTH IN THE 21ST CENTURY: BONE AND BEYOND |
1 From Creighton University Medical Center, Omaha
ABSTRACT
Serum 25-hydroxyvitamin D3 [25(OH)D3] concentrations are currently recognized as the functional status indicator for vitamin D. Evidence is reviewed that shows that serum 25(OH)D3 concentrations of < 80 nmol/L are associated with reduced calcium absorption, osteoporosis, and increased fracture risk. For typical older individuals, supplemental oral intakes of 
1300 IU/d are required to reach the lower end of the optimal range. Evidence of substantial problems in routine clinical measurement of serum 25(OH)D3 concentrations among patients is cited. There is great need for standardization and improved reproducibility and sensitivity of measurements of serum 25(OH)D3 concentrations.
Key Words: Rickets • osteomalacia • osteoporosis • calcium absorption • fractures • serum 25-hydroxyvitamin D3
This article has been cited by other articles:
|
|
 |
|
  D. J. Llewellyn, K. M. Langa, and I. A. Lang Serum 25-Hydroxyvitamin D Concentration and Cognitive Impairment J Geriatr Psychiatry Neurol, September 1, 2009; 22(3): 188 - 195. [Abstract] [PDF]
|
|
|
|
 |
|
 K. M Seamans and K. D Cashman Existing and potentially novel functional markers of vitamin D status: a systematic review Am. J. Clinical Nutrition, June 1, 2009; 89(6): 1997S - 2008S. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. M. Gordon, H. A. Feldman, and J. E. Cox Vitamin D and Rickets Beyond America--Reply Arch Pediatr Adolesc Med, December 1, 2008; 162(12): 1194 - 1194. [Full Text] [PDF]
|
|
|
|
 |
|
 C. H Halsted Perspectives on obesity and sweeteners, folic acid fortification and vitamin D requirements Fam. Pract., December 1, 2008; 25(suppl_1): i44 - i49. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. L. Gardner, F. Harris, E. Vittinghoff, and S. R. Cummings The Risk of Fracture Following Hospitalization in Older Women and Men Arch Intern Med, August 11, 2008; 168(15): 1671 - 1677. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. M. Gordon, H. A. Feldman, L. Sinclair, A. L. Williams, P. K. Kleinman, J. Perez-Rossello, and J. E. Cox Prevalence of Vitamin D Deficiency Among Healthy Infants and Toddlers Arch Pediatr Adolesc Med, June 1, 2008; 162(6): 505 - 512. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Rovner and K. O. O'Brien Hypovitaminosis D Among Healthy Children in the United States: A Review of the Current Evidence Arch Pediatr Adolesc Med, June 1, 2008; 162(6): 513 - 519. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A Talwar, J. F Aloia, S. Pollack, and J. K Yeh Dose response to vitamin D supplementation among postmenopausal African American women Am. J. Clinical Nutrition, December 1, 2007; 86(6): 1657 - 1662. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Matusiak and R. V. Benya CYP27A1 and CYP24 Expression as a Function of Malignant Transformation in the Colon J. Histochem. Cytochem., December 1, 2007; 55(12): 1257 - 1264. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Giovannucci Can Vitamin D Reduce Total Mortality? Arch Intern Med, September 10, 2007; 167(16): 1709 - 1710. [Full Text] [PDF]
|
|
|
|
|
|
F. L Weng, J. Shults, M. B Leonard, V. A Stallings, and B. S Zemel Risk factors for low serum 25-hydroxyvitamin D concentrations in otherwise healthy children and adolescents Am. J. Clinical Nutrition, July 1, 2007; 86(1): 150 - 158. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. F. Lata and M. E. Elliott Patient Assessment in the Diagnosis, Prevention, and Treatment of Osteoporosis Nutr Clin Pract, June 1, 2007; 22(3): 261 - 275. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Shinchuk and M. F. Holick Vitamin D and Rehabilitation: Improving Functional Outcomes Nutr Clin Pract, June 1, 2007; 22(3): 297 - 304. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. K. Houston, M. Cesari, L. Ferrucci, A. Cherubini, D. Maggio, B. Bartali, M. A. Johnson, G. G. Schwartz, and S. B. Kritchevsky Association Between Vitamin D Status and Physical Performance: The InCHIANTI Study J. Gerontol. A Biol. Sci. Med. Sci., April 1, 2007; 62(4): 440 - 446. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Grote Vitamin D Deficiency JAMA, March 1, 2006; 295(9): 1002 - 1002. [Full Text] [PDF]
|
|
|
|
 |
|
 M. F. Holick High Prevalence of Vitamin D Inadequacy and Implications for Health Mayo Clin. Proc., March 1, 2006; 81(3): 353 - 373. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. M Stein, E. M Laing, D. B Hall, D. B Hausman, M. G Kimlin, M. A. Johnson, C. M Modlesky, A. R Wilson, and R. D Lewis Serum 25-hydroxyvitamin D concentrations in girls aged 4-8 y living in the southeastern United States Am. J. Clinical Nutrition, January 1, 2006; 83(1): 75 - 81. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Nakamura, K. Ueno, T. Nishiwaki, Y. Okuda, T. Saito, Y. Tsuchiya, and M. Yamamoto Nutrition, mild hyperparathyroidism, and bone mineral density in young Japanese women Am. J. Clinical Nutrition, November 1, 2005; 82(5): 1127 - 1133. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. A. Tylavsky, K. A. Ryder, A. Lyytikainen, and S. Cheng Vitamin D, Parathyroid Hormone, and Bone Mass in Adolescents J. Nutr., November 1, 2005; 135(11): 2735S - 2738S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. A. Bischoff-Ferrari, W. C. Willett, J. B. Wong, E. Giovannucci, T. Dietrich, and B. Dawson-Hughes Fracture Prevention With Vitamin D Supplementation: A Meta-analysis of Randomized Controlled Trials JAMA, May 11, 2005; 293(18): 2257 - 2264. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Seeman and G. J. Strewler Clinical and Basic Research Papers - December 2004 Selections IBMS BoneKEy, January 1, 2005; 2(1): 1 - 5. [Full Text] [PDF]
|
|
|
|
|
|
D. J Raiten and M. F. Picciano Vitamin D and health in the 21st century: bone and beyond. Executive summary Am. J. Clinical Nutrition, December 1, 2004; 80(6): 1673S - 1677S. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
