| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
ORIGINAL RESEARCH COMMUNICATION |
1 From the Program in International Nutrition and the Department of Nutrition, University of California, Davis (DLdR, JMP, and KHB); the Instituto de Investigación Nutricional, Lima, Perú (DLdR, MS, and MEP); the Section of Nutrition, Department of Pediatrics, University of Colorado, Denver (KMH and NFK).
Background:Information is needed on the fractional absorption of zinc (FAZ) and absorbed zinc (AZ) during prolonged exposure to zinc-fortified foods.
Objective:The objective was to measure FAZ and AZ from diets fortified with different amounts of zinc and to determine whether zinc absorption changes over 
7 wk.
Design:Forty-one stunted, moderately anemic children received daily, at breakfast and lunch, 100 g wheat products fortified with 3 mg Fe (ferrous sulfate) and 0 (group Zn-0), 3 (group Zn-3), or 9 (group Zn-9) mg Zn (zinc sulfate) per 100 g flour. FAZ was measured on days 2–3 and 51–52; meal-specific AZs were calculated as the product of FAZ and zinc intake.
Results:For the breakfast and lunch meals combined, mean total zinc intakes were 2.14, 4.72, and 10.04 mg/d in groups Zn-0, Zn-3, and Zn-9, respectively, during the initial absorption studies; mean (±SD) FAZ values were 0.341 ± 0.111, 0.237 ± 0.052, and 0.133 ± 0.041, respectively, on days 2–3 (P < 0.001) and did not change significantly on days 51–52 in the subset of 31 children studied twice. Mean initial AZ was positively related to zinc intake (0.71 ± 0.18, 1.11 ± 0.21, and 1.34 ± 0.47 mg/d, respectively; P < 0.001); final values did not differ significantly from the initial values.
Conclusions:AZ from meals containing zinc-fortified wheat products increases in young children relative to the level of fortification and changes only slightly during 7-wk periods of consumption. Although consumption of zinc-fortified foods may reduce FAZ, zinc fortification at the levels studied positively affects total daily zinc absorption, even after nearly 2 mo of exposure to zinc-fortified diets.
Key Words: Zinc • iron • wheat • fortification • absorption • stable isotopes • children
This article has been cited by other articles:
|
|
 |
|
  C. S Chung, J. Stookey, D. Dare, R. Welch, T. Q Nguyen, R. Roehl, J. M Peerson, J. C King, and K. H Brown Current dietary zinc intake has a greater effect on fractional zinc absorption than does longer term zinc consumption in healthy adult men Am. J. Clinical Nutrition, May 1, 2008; 87(5): 1224 - 1229. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. E Wuehler, F. Sempertegui, and K. H Brown Dose-response trial of prophylactic zinc supplements, with or without copper, in young Ecuadorian children at risk of zinc deficiency Am. J. Clinical Nutrition, March 1, 2008; 87(3): 723 - 733. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Etcheverry, G. E Carstens, E. Brown, K. M Hawthorne, Z. Chen, and I. J Griffin Production of stable-isotope-labeled bovine heme and its use to measure heme-iron absorption in children Am. J. Clinical Nutrition, February 1, 2007; 85(2): 452 - 459. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. H Brown, D. L. de Romana, J. E Arsenault, J. M Peerson, and M. E Penny Comparison of the effects of zinc delivered in a fortified food or a liquid supplement on the growth, morbidity, and plasma zinc concentrations of young Peruvian children Am. J. Clinical Nutrition, February 1, 2007; 85(2): 538 - 547. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X.-Y. Sheng, K M. Hambidge, X.-X. Zhu, J.-X. Ni, K. B Bailey, R. S Gibson, and N. F Krebs Major variables of zinc homeostasis in Chinese toddlers. Am. J. Clinical Nutrition, August 1, 2006; 84(2): 389 - 394. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. H. Allen New Approaches for Designing and Evaluating Food Fortification Programs J. Nutr., April 1, 2006; 136(4): 1055 - 1058. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
