| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
ORIGINAL RESEARCH COMMUNICATION |
1 From the Departments of Foods and Nutrition (EMS, EML, DBH, MAJ, ARW, and RDL) and Statistics (DBH), the University of Georgia, Athens, GA; the Center for Public Health Research, School of Public Health, Queensland University of Technology, Brisbane, Australia (MGK); and the Department of Health, Nutrition, and Exercise Sciences, University of Delaware, Newark, DE (CMM)
Background: Evidence suggests that adults and adolescents throughout the United States are at risk of poor vitamin D status. However, vitamin D concentrations in young American children have not been assessed.
Objective: The relations between serum 25-hydroxyvitamin D [25(OH)D] and bone were examined in prepubertal girls.
Design: In the present cross-sectional study, serum 25(OH)D concentration was assessed in 168 prepubertal girls aged 4–8 y living in the southeastern United States with the use of radioimmunoassay. Bone area, bone mineral content, and areal bone mineral density were measured from total body, lumbar spine, proximal femur, and forearm with dual-energy X-ray absorptiometry. Data were analyzed with analysis of variance, analysis of covariance, stepwise multiple regression, and partial correlations.
Results: The mean (±SD) serum 25(OH)D was 93.8 ± 28.1 nmol/L (range: 31.1–181.4 nmol/L). In a multiple regression analysis, race and season were the strongest predictors of vitamin D status. The black girls had lower mean 25(OH)D values than did the white girls (P < 0.01), and 25(OH)D values were significantly different in the total sample between the seasons (P < 0.001), ranging from 74.4 nmol/L during the winter months to 107 nmol/L during the summer. After adjustment for season, age, race, and body mass index, 25(OH)D values were negatively correlated with forearm bone mineral content (r = –0.18; P = 0.02).
Conclusions: Unlike prior reports of adults and adolescents living in the southeastern United States, vitamin D status was adequate in the children of the present study. 25(OH)D concentrations were not positively associated with higher bone mineral.
Key Words: Serum 25-hydroxyvitamin D • prepubertal girls • Georgia • race • season • bone mineral • body composition
This article has been cited by other articles:
|
|
 |
|
  C. M. Weaver, L. D. McCabe, G. P. McCabe, M. Braun, B. R. Martin, L. A. DiMeglio, and M. Peacock Vitamin D Status and Calcium Metabolism in Adolescent Black and White Girls on a Range of Controlled Calcium Intakes J. Clin. Endocrinol. Metab., October 1, 2008; 93(10): 3907 - 3914. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Misra, D. Pacaud, A. Petryk, P. F. Collett-Solberg, M. Kappy, and on behalf of the Drug and Therapeutics Committee o Vitamin D Deficiency in Children and Its Management: Review of Current Knowledge and Recommendations Pediatrics, August 1, 2008; 122(2): 398 - 417. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. J. Rovner and K. O. O'Brien Hypovitaminosis D Among Healthy Children in the United States: A Review of the Current Evidence Arch Pediatr Adolesc Med, June 1, 2008; 162(6): 513 - 519. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. L Weng, J. Shults, M. B Leonard, V. A Stallings, and B. S Zemel Risk factors for low serum 25-hydroxyvitamin D concentrations in otherwise healthy children and adolescents Am. J. Clinical Nutrition, July 1, 2007; 86(1): 150 - 158. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Vieth, H. Bischoff-Ferrari, B. J Boucher, B. Dawson-Hughes, C. F Garland, R. P Heaney, M. F Holick, B. W Hollis, C. Lamberg-Allardt, J. J McGrath, et al. The urgent need to recommend an intake of vitamin D that is effective Am. J. Clinical Nutrition, March 1, 2007; 85(3): 649 - 650. [Full Text] [PDF]
|
|
|
|
|
|
C. M Willis, E. M Laing, D. B Hall, D. B Hausman, and R. D Lewis A prospective analysis of plasma 25-hydroxyvitamin D concentrations in white and black prepubertal females in the southeastern United States Am. J. Clinical Nutrition, January 1, 2007; 85(1): 124 - 130. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
