HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by López-Huertas, E. Articles by Fairweather-Tait, S. Search for Related Content PubMed PubMed Citation Articles by López-Huertas, E. Articles by Fairweather-Tait, S. Agricola Articles by López-Huertas, E. Articles by Fairweather-Tait, S.

Absorption of calcium from milks enriched with fructo-oligosaccharides, caseinophosphopeptides, tricalcium phosphate, and milk solids^1,2,3

¹ From the Institute of Food Research, Norwich, United Kingdom (BT, SFT, and GM-N); Puleva Biotech SA,Granada, Spain (ELH, JJB, AMF, MGS, and JF); the Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Granada, Granada, Spain (JJC); and Distrito Sanitario Costa del Sol, Servicio Andaluz de Salud, Málaga, Spain (LB)

Background: Adequate intakes of calcium are required for optimal bone health and protection against chronic disease. Dairy products are an excellent source of calcium.

Objective: The absorption of calcium from a range of fortified milks was measured in humans with the use of stable isotopes.

Design: Fifteen volunteers participated in a randomized, controlled, double-blind crossover study. Five types of semi-skimmed (1.9% fat) milk drinks were administered with a light breakfast: standard milk (control milk); milk enriched with calcium from milk solids and tricalcium phosphate [(TCP) MSS milk]; milk enriched with calcium from concentrated milk (CON milk); milk with added fructo-oligosaccharides [(FOSs) FOS milk]; and milk with added caseinophosphopeptides [(CPPs) CPP milk]. All the milks were labeled with ⁴²Ca as CaCl₂. The MSS milk was also labeled with ⁴⁴Ca as TCP. The quantity of calcium in each drink was kept the same by varying the volume given.

Results: Calcium absorption did not differ significantly between the control milk and the calcium-fortified milks (MSS and CON milk) or the FOS and CPP milks. However, calcium absorption from the TCP added to the MSS milk was significantly higher than that from the control milk (27.5 ± 7.6% and 24.5 ± 7.3%, respectively; P = 0.003).

Conclusions: Calcium-enriched milks are a valuable source of well-absorbed calcium. Absorption of added calcium as TCP was higher than that of calcium from the control milk, but the addition of FOSs or CPPs did not significantly increase calcium absorption. Further research is needed to ascertain the cost-effectiveness and public health benefits of consuming fortified milks.

Key Words: Calcium • stable isotope • absorption • milk • fortification • tricalcium phosphate • fructo-oligosaccharides • caseinophosphopeptides

This article has been cited by other articles:

				H. Tanimoto, T. Fox, J. Eagles, H. Satoh, H. Nozawa, A. Okiyama, Y. Morinaga, and S. J. Fairweather-Tait Acute Effect of Poly-{gamma}-Glutamic Acid on Calcium Absorption in Post-Menopausal Women J. Am. Coll. Nutr., December 1, 2007; 26(6): 645 - 649. [Abstract] [Full Text] [PDF]

				K. E. Scholz-Ahrens, P. Ade, B. Marten, P. Weber, W. Timm, Y. A{varsigma}il, C.-C. Gluer, and J. Schrezenmeir Prebiotics, Probiotics, and Synbiotics Affect Mineral Absorption, Bone Mineral Content, and Bone Structure J. Nutr., March 1, 2007; 137(3): 838S - 846S. [Abstract] [Full Text] [PDF]

				B. Teucher, G. Majsak-Newman, J. R Dainty, D. McDonagh, R. J FitzGerald, and S. J Fairweather-Tait Calcium absorption is not increased by caseinophosphopeptides Am. J. Clinical Nutrition, July 1, 2006; 84(1): 162 - 166. [Abstract] [Full Text] [PDF]