AJCN EB Program 2010
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow An erratum has been published
Right arrow An erratum has been published
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bischoff-Ferrari, H. A
Right arrow Articles by Dawson-Hughes, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bischoff-Ferrari, H. A
Right arrow Articles by Dawson-Hughes, B.
Agricola
Right arrow Articles by Bischoff-Ferrari, H. A
Right arrow Articles by Dawson-Hughes, B.
American Journal of Clinical Nutrition, Vol. 84, No. 1, 18-28, July 2006
© 2006 American Society for Nutrition

REVIEW ARTICLE

Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes1,2,3

Heike A Bischoff-Ferrari, Edward Giovannucci, Walter C Willett, Thomas Dietrich and Bess Dawson-Hughes

1 From the Department of Nutrition, Harvard School of Public Health, Boston, MA (HAB-F, EG, and WCW); the Department of Rheumatology and the Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland (HAB-F); the Department of Epidemiology and the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, MA (EG and WCW); the Department of Health Policy and Health Services Research, Boston University Goldman School of Dental Medicine, Boston, MA (TD); and the Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA (BD-H)

Recent evidence suggests that vitamin D intakes above current recommendations may be associated with better health outcomes. However, optimal serum concentrations of 25-hydroxyvitamin D [25(OH)D] have not been defined. This review summarizes evidence from studies that evaluated thresholds for serum 25(OH)D concentrations in relation to bone mineral density (BMD), lower-extremity function, dental health, and risk of falls, fractures, and colorectal cancer. For all endpoints, the most advantageous serum concentrations of 25(OH)D begin at 75 nmol/L (30 ng/mL), and the best are between 90 and 100 nmol/L (36–40 ng/mL). In most persons, these concentrations could not be reached with the currently recommended intakes of 200 and 600 IU vitamin D/d for younger and older adults, respectively. A comparison of vitamin D intakes with achieved serum concentrations of 25(OH)D for the purpose of estimating optimal intakes led us to suggest that, for bone health in younger adults and all studied outcomes in older adults, an increase in the currently recommended intake of vitamin D is warranted. An intake for all adults of ≥1000 IU (40 µg) vitamin D (cholecalciferol)/d is needed to bring vitamin D concentrations in no less than 50% of the population up to 75 nmol/L. The implications of higher doses for the entire adult population should be addressed in future studies.

Key Words: 25-Hydroxyvitamin D • vitamin D intake • bone density • lower-extremity strength • colorectal cancer




This article has been cited by other articles:


Home page
 Am. J. Clin. Nutr.Home page
S B. Eaton, M. J Konner, and L. Cordain
Diet-dependent acid load, Paleolithic nutrition, and evolutionary health promotion
Am. J. Clinical Nutrition, February 1, 2010; 91(2): 295 - 297.
[Full Text] [PDF]

Home page
 J Trop PediatrHome page
A. T. Soliman, M. El-Dabbagh, A. Adel, M. A. Ali, E. M. Aziz Bedair, and R. K. ElAlaily
Clinical Responses to a Mega-dose of Vitamin D3 in Infants and Toddlers With Vitamin D Deficiency Rickets
J Trop Pediatr, February 1, 2010; 56(1): 19 - 26.
[Abstract] [Full Text] [PDF]

Home page
 BMJHome page
J. K Y Lam, K. S L Lam, K. C B Tan, W.-S. Chow, A. W K Tso, and A. W C Kung
A woman with hypophosphataemia and raised alkaline phosphatase
BMJ, January 20, 2010; 340(jan20_1): b5564 - b5564.
[Full Text]

Home page
 BMJHome page
The DIPART (vitamin D Individual Patient Analysis
Patient level pooled analysis of 68 500 patients from seven major vitamin D fracture trials in US and Europe
BMJ, January 12, 2010; 340(jan12_1): b5463 - b5463.
[Abstract] [Full Text] [PDF]

Home page
 BMJHome page
S. H. Pearce and T. D Cheetham
Diagnosis and management of vitamin D deficiency
BMJ, January 11, 2010; 340(jan11_1): b5664 - b5664.
[Full Text]

Home page
 AMERICAN JOURNAL OF LIFESTYLE MEDICINEHome page
M. A. Johnson, M. G. Kimlin, and K. N. Porter
Vitamin D and Injury Prevention
American Journal of Lifestyle Medicine, January 1, 2010; 4(1): 21 - 24.
[Abstract] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
M. J Bolland, C. J Bacon, A. M Horne, B. H Mason, R. W Ames, T. K. Wang, A. B Grey, G. D Gamble, and I. R Reid
Vitamin D insufficiency and health outcomes over 5 y in older women
Am. J. Clinical Nutrition, January 1, 2010; 91(1): 82 - 89.
[Abstract] [Full Text] [PDF]

Home page
 JPEN J Parenter Enteral NutrHome page
A. G. Pittas, U. Laskowski, L. Kos, and E. Saltzman
Role of Vitamin D in Adults Requiring Nutrition Support
JPEN J Parenter Enteral Nutr, January 1, 2010; 34(1): 70 - 78.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
D L. Alekel, M. D Van Loan, K. J Koehler, L. N Hanson, J. W Stewart, K. B Hanson, M. S Kurzer, and C T. Peterson
The Soy Isoflavones for Reducing Bone Loss (SIRBL) Study: a 3-y randomized controlled trial in postmenopausal women
Am. J. Clinical Nutrition, January 1, 2010; 91(1): 218 - 230.
[Abstract] [Full Text] [PDF]

Home page
 Age AgeingHome page
V. Hirani, K. Tull, A. Ali, and J. Mindell
Urgent action needed to improve vitamin D status among older people in England!
Age Ageing, January 1, 2010; 39(1): 62 - 68.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
S. Kukuljan, C. A. Nowson, K. Sanders, and R. M. Daly
Effects of resistance exercise and fortified milk on skeletal muscle mass, muscle size, and functional performance in middle-aged and older men: an 18-mo randomized controlled trial
J Appl Physiol, December 1, 2009; 107(6): 1864 - 1873.
[Abstract] [Full Text] [PDF]

Home page
 QJMHome page
M.R. Goldstein, L. Mascitelli, and F. Pezzetta
Statin therapy, muscle function and vitamin D
QJM, December 1, 2009; 102(12): 890 - 891.
[Full Text] [PDF]

Home page
 PediatricsHome page
J. M. Mansbach, A. A. Ginde, and C. A. Camargo Jr
Serum 25-Hydroxyvitamin D Levels Among US Children Aged 1 to 11 Years: Do Children Need More Vitamin D?
Pediatrics, November 1, 2009; 124(5): 1404 - 1410.
[Abstract] [Full Text] [PDF]

Home page
 Am J EpidemiolHome page
A. Kilkkinen, P. Knekt, A. Aro, H. Rissanen, J. Marniemi, M. Heliovaara, O. Impivaara, and A. Reunanen
Vitamin D Status and the Risk of Cardiovascular Disease Death
Am. J. Epidemiol., October 15, 2009; 170(8): 1032 - 1039.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
O. Tarcin, D. G. Yavuz, B. Ozben, A. Telli, A. V. Ogunc, M. Yuksel, A. Toprak, D. Yazici, S. Sancak, O. Deyneli, et al.
Effect of Vitamin D Deficiency and Replacement on Endothelial Function in Asymptomatic Subjects
J. Clin. Endocrinol. Metab., October 1, 2009; 94(10): 4023 - 4030.
[Abstract] [Full Text] [PDF]

Home page
 AMERICAN JOURNAL OF LIFESTYLE MEDICINEHome page
C. D. Davis
Vitamin D and Health: Can Too Much Be Harmful?
American Journal of Lifestyle Medicine, September 1, 2009; 3(5): 407 - 408.
[PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
T. D. Thacher, M. O. Obadofin, K. O. O'Brien, and S. A. Abrams
The Effect of Vitamin D2 and Vitamin D3 on Intestinal Calcium Absorption in Nigerian Children with Rickets
J. Clin. Endocrinol. Metab., September 1, 2009; 94(9): 3314 - 3321.
[Abstract] [Full Text] [PDF]

Home page
 Age AgeingHome page
A. Avenell, J. A. Cook, G. S. MacLennan, and G. C. McPherson
Vitamin D supplementation and type 2 diabetes: a substudy of a randomised placebo-controlled trial in older people (RECORD trial, ISRCTN 51647438)
Age Ageing, September 1, 2009; 38(5): 606 - 609.
[Full Text] [PDF]

Home page
 Anticancer ResHome page
B. NURNBERG, S. GRABER, B. GARTNER, J. GEISEL, C. PFOHLER, D. SCHADENDORF, W. TILGEN, and J. REICHRATH
Reduced Serum 25-Hydroxyvitamin D Levels in Stage IV Melanoma Patients
Anticancer Res, September 1, 2009; 29(9): 3669 - 3674.
[Abstract] [Full Text] [PDF]

Home page
 Anticancer ResHome page
M. PETERLIK, W. B. GRANT, and H. S. CROSS
Calcium, Vitamin D and Cancer
Anticancer Res, September 1, 2009; 29(9): 3687 - 3698.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
J. Kumar, P. Muntner, F. J. Kaskel, S. M. Hailpern, and M. L. Melamed
Prevalence and Associations of 25-Hydroxyvitamin D Deficiency in US Children: NHANES 2001-2004
Pediatrics, September 1, 2009; 124(3): e362 - e370.
[Abstract] [Full Text] [PDF]

Home page
 JCOHome page
P. J. Goodwin, M. Ennis, K. I. Pritchard, J. Koo, and N. Hood
Prognostic Effects of 25-Hydroxyvitamin D Levels in Early Breast Cancer
J. Clin. Oncol., August 10, 2009; 27(23): 3757 - 3763.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
J R Tucci
Vitamin D therapy in patients with primary hyperparathyroidism and hypovitaminosis D
Eur. J. Endocrinol., July 1, 2009; 161(1): 189 - 193.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
K. D Cashman, J. M. Wallace, G. Horigan, T. R Hill, M. S Barnes, A. J Lucey, M. P Bonham, N. Taylor, E. M Duffy, K. Seamans, et al.
Estimation of the dietary requirement for vitamin D in free-living adults >=64 y of age
Am. J. Clinical Nutrition, May 1, 2009; 89(5): 1366 - 1374.
[Abstract] [Full Text] [PDF]

Home page
 JCOHome page
K. D. Crew, E. Shane, S. Cremers, D. J. McMahon, D. Irani, and D. L. Hershman
High Prevalence of Vitamin D Deficiency Despite Supplementation in Premenopausal Women With Breast Cancer Undergoing Adjuvant Chemotherapy
J. Clin. Oncol., May 1, 2009; 27(13): 2151 - 2156.
[Abstract] [Full Text] [PDF]

Home page
 JCOHome page
P. J. Goodwin
Vitamin D in Cancer Patients: Above All, Do No Harm
J. Clin. Oncol., May 1, 2009; 27(13): 2117 - 2119.
[Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
J. M. Brehm, J. C. Celedon, M. E. Soto-Quiros, L. Avila, G. M. Hunninghake, E. Forno, D. Laskey, J. S. Sylvia, B. W. Hollis, S. T. Weiss, et al.
Serum Vitamin D Levels and Markers of Severity of Childhood Asthma in Costa Rica
Am. J. Respir. Crit. Care Med., May 1, 2009; 179(9): 765 - 771.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
W. Janssens, A. Lehouck, C. Carremans, R. Bouillon, C. Mathieu, and M. Decramer
Vitamin D Beyond Bones in Chronic Obstructive Pulmonary Disease: Time to Act
Am. J. Respir. Crit. Care Med., April 15, 2009; 179(8): 630 - 636.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
M. F. Holick
MrOs Is D-ficient
J. Clin. Endocrinol. Metab., April 1, 2009; 94(4): 1092 - 1093.
[Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
N. O. Kuchuk, S. M. F. Pluijm, N. M. van Schoor, C. W. N. Looman, J. H. Smit, and P. Lips
Relationships of Serum 25-Hydroxyvitamin D to Bone Mineral Density and Serum Parathyroid Hormone and Markers of Bone Turnover in Older Persons
J. Clin. Endocrinol. Metab., April 1, 2009; 94(4): 1244 - 1250.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
S. M Smith, K. K Gardner, J. Locke, and S. R Zwart
Vitamin D supplementation during Antarctic winter
Am. J. Clinical Nutrition, April 1, 2009; 89(4): 1092 - 1098.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
V. Mocanu, P. A Stitt, A. R. Costan, O. Voroniuc, E. Zbranca, V. Luca, and R. Vieth
Long-term effects of giving nursing home residents bread fortified with 125 {micro}g (5000 IU) vitamin D3 per daily serving
Am. J. Clinical Nutrition, April 1, 2009; 89(4): 1132 - 1137.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
A. A. Ginde, M. C. Liu, and C. A. Camargo Jr
Demographic Differences and Trends of Vitamin D Insufficiency in the US Population, 1988-2004
Arch Intern Med, March 23, 2009; 169(6): 626 - 632.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
A. Merewood, S. D. Mehta, T. C. Chen, H. Bauchner, and M. F. Holick
Association between Vitamin D Deficiency and Primary Cesarean Section
J. Clin. Endocrinol. Metab., March 1, 2009; 94(3): 940 - 945.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
E. A Yetley, D. Brule, M. C Cheney, C. D Davis, K. A Esslinger, P. W. Fischer, K. E Friedl, L. S Greene-Finestone, P. M Guenther, D. M Klurfeld, et al.
Dietary Reference Intakes for vitamin D: justification for a review of the 1997 values
Am. J. Clinical Nutrition, March 1, 2009; 89(3): 719 - 727.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
A. A. Ginde, J. M. Mansbach, and C. A. Camargo Jr
Association Between Serum 25-Hydroxyvitamin D Level and Upper Respiratory Tract Infection in the Third National Health and Nutrition Examination Survey
Arch Intern Med, February 23, 2009; 169(4): 384 - 390.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
R. Eastell, A. Arnold, M. L. Brandi, E. M. Brown, P. D'Amour, D. A. Hanley, D. S. Rao, M. R. Rubin, D. Goltzman, S. J. Silverberg, et al.
Diagnosis of Asymptomatic Primary Hyperparathyroidism: Proceedings of the Third International Workshop
J. Clin. Endocrinol. Metab., February 1, 2009; 94(2): 340 - 350.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
E. Giovannucci
Expanding Roles of Vitamin D
J. Clin. Endocrinol. Metab., February 1, 2009; 94(2): 418 - 420.
[Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
R. Kremer, P. P. Campbell, T. Reinhardt, and V. Gilsanz
Vitamin D Status and Its Relationship to Body Fat, Final Height, and Peak Bone Mass in Young Women
J. Clin. Endocrinol. Metab., January 1, 2009; 94(1): 67 - 73.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
S. M. Arpadi, D. McMahon, E. J. Abrams, M. Bamji, M. Purswani, E. S. Engelson, M. Horlick, and E. Shane
Effect of Bimonthly Supplementation With Oral Cholecalciferol on Serum 25-Hydroxyvitamin D Concentrations in HIV-Infected Children and Adolescents
Pediatrics, January 1, 2009; 123(1): e121 - e126.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J. H. Lee, J. H. O'Keefe, D. Bell, D. D. Hensrud, and M. F. Holick
Vitamin D Deficiency: An Important, Common, and Easily Treatable Cardiovascular Risk Factor?
J. Am. Coll. Cardiol., December 9, 2008; 52(24): 1949 - 1956.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
M Sneve, Y Figenschau, and R Jorde
Supplementation with cholecalciferol does not result in weight reduction in overweight and obese subjects
Eur. J. Endocrinol., December 1, 2008; 159(6): 675 - 684.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
S. O'Donnell, A. Cranney, T. Horsley, H. A Weiler, S. A Atkinson, D. A Hanley, D. S Ooi, L. Ward, N. Barrowman, M. Fang, et al.
Efficacy of food fortification on serum 25-hydroxyvitamin D concentrations: systematic review
Am. J. Clinical Nutrition, December 1, 2008; 88(6): 1528 - 1534.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
K. D Cashman, T. R Hill, A. J Lucey, N. Taylor, K. M Seamans, S. Muldowney, A. P FitzGerald, A. Flynn, M. S Barnes, G. Horigan, et al.
Estimation of the dietary requirement for vitamin D in healthy adults
Am. J. Clinical Nutrition, December 1, 2008; 88(6): 1535 - 1542.
[Abstract] [Full Text] [PDF]

Home page
 J. Am. Coll. Nutr.Home page
W. A. van Staveren, J. M. Steijns, and L. C.P.G.M. de Groot
Dairy Products as Essential Contributors of (Micro-) Nutrients in Reference Food Patterns: An Outline for Elderly People
J. Am. Coll. Nutr., December 1, 2008; 27(6): 747S - 754S.
[Abstract] [Full Text] [PDF]

Home page
 Fam PractHome page
C. H Halsted
Perspectives on obesity and sweeteners, folic acid fortification and vitamin D requirements
Fam. Pract., December 1, 2008; 25(suppl_1): i44 - i49.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
C. L. Wagner, F. R. Greer, and and the Section on Breastfeeding and Committee on
Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents
Pediatrics, November 1, 2008; 122(5): 1142 - 1152.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
D.-H. Manicourt and J.-P. Devogelaer
Urban Tropospheric Ozone Increases the Prevalence of Vitamin D Deficiency among Belgian Postmenopausal Women with Outdoor Activities during Summer
J. Clin. Endocrinol. Metab., October 1, 2008; 93(10): 3893 - 3899.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
S. Pilz, W. Marz, B. Wellnitz, U. Seelhorst, A. Fahrleitner-Pammer, H. P. Dimai, B. O. Boehm, and H. Dobnig
Association of Vitamin D Deficiency with Heart Failure and Sudden Cardiac Death in a Large Cross-Sectional Study of Patients Referred for Coronary Angiography
J. Clin. Endocrinol. Metab., October 1, 2008; 93(10): 3927 - 3935.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
D. E. Wallis, S. Penckofer, and G. W. Sizemore
The "Sunshine Deficit" and Cardiovascular Disease
Circulation, September 30, 2008; 118(14): 1476 - 1485.
[Full Text] [PDF]

Home page
 Am J EpidemiolHome page
R. Scragg and C. A. Camargo Jr.
Frequency of Leisure-Time Physical Activity and Serum 25-Hydroxyvitamin D Levels in the US Population: Results from the Third National Health and Nutrition Examination Survey
Am. J. Epidemiol., September 15, 2008; 168(6): 577 - 586.
[Abstract] [Full Text] [PDF]

Home page
 Am J EpidemiolHome page
R. Scragg and C. A. Camargo Jr
Scragg and Camargo Respond to "Physical Activity and Vitamin D"
Am. J. Epidemiol., September 15, 2008; 168(6): 590 - 591.
[Full Text] [PDF]

Home page
 Infect. Immun.Home page
J. H. White
Vitamin D Signaling, Infectious Diseases, and Regulation of Innate Immunity
Infect. Immun., September 1, 2008; 76(9): 3837 - 3843.
[Full Text] [PDF]

Home page
 J. Nutr.Home page
R. P. Heaney
Nutrients, Endpoints, and the Problem of Proof
J. Nutr., September 1, 2008; 138(9): 1591 - 1595.
[Full Text] [PDF]

Home page
 StrokeHome page
S. Pilz, H. Dobnig, J. E. Fischer, B. Wellnitz, U. Seelhorst, B. O. Boehm, and W. Marz
Low Vitamin D Levels Predict Stroke in Patients Referred to Coronary Angiography
Stroke, September 1, 2008; 39(9): 2611 - 2613.
[Abstract] [Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
B. J. Jones and P. J. Twomey
Issues with vitamin D in routine clinical practice
Rheumatology, September 1, 2008; 47(9): 1267 - 1268.
[Full Text] [PDF]

Home page
 Arch Intern MedHome page
M. L. Melamed, E. D. Michos, W. Post, and B. Astor
25-Hydroxyvitamin D Levels and the Risk of Mortality in the General Population
Arch Intern Med, August 11, 2008; 168(15): 1629 - 1637.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
S.-M. Orton, A. P Morris, B. M Herrera, S. V Ramagopalan, M. R Lincoln, M. J Chao, R. Vieth, A D. Sadovnick, and G. C Ebers
Evidence for genetic regulation of vitamin D status in twins with multiple sclerosis
Am. J. Clinical Nutrition, August 1, 2008; 88(2): 441 - 447.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
A. Prentice, G. R Goldberg, and I. Schoenmakers
Vitamin D across the lifecycle: physiology and biomarkers
Am. J. Clinical Nutrition, August 1, 2008; 88(2): 500S - 506S.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
E. A Yetley
Assessing the vitamin D status of the US population
Am. J. Clinical Nutrition, August 1, 2008; 88(2): 558S - 564S.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
B. Hintzpeter, C. Scheidt-Nave, M. J. Muller, L. Schenk, and G. B. M. Mensink
Higher Prevalence of Vitamin D Deficiency Is Associated with Immigrant Background among Children and Adolescents in Germany
J. Nutr., August 1, 2008; 138(8): 1482 - 1490.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Chem.Home page
S. Mark, K. Gray-Donald, E. E. Delvin, J. O'Loughlin, G. Paradis, E. Levy, and M. Lambert
Low Vitamin D Status in a Representative Sample of Youth From Quebec, Canada
Clin. Chem., August 1, 2008; 54(8): 1283 - 1289.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
M. L Neuhouser, B. Sorensen, B. W Hollis, A. Ambs, C. M Ulrich, A. McTiernan, L. Bernstein, S. Wayne, F. Gilliland, K. Baumgartner, et al.
Vitamin D insufficiency in a multiethnic cohort of breast cancer survivors
Am. J. Clinical Nutrition, July 1, 2008; 88(1): 133 - 139.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
D. Wagner, G. Sidhom, S. J. Whiting, D. Rousseau, and R. Vieth
The Bioavailability of Vitamin D from Fortified Cheeses and Supplements Is Equivalent in Adults
J. Nutr., July 1, 2008; 138(7): 1365 - 1371.
[Abstract] [Full Text] [PDF]

Home page
 CJASNHome page
R. Mehrotra, D. Kermah, M. Budoff, I. B. Salusky, S. S. Mao, Y. L. Gao, J. Takasu, S. Adler, and K. Norris
Hypovitaminosis D in Chronic Kidney Disease
Clin. J. Am. Soc. Nephrol., July 1, 2008; 3(4): 1144 - 1151.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
H. Dobnig, S. Pilz, H. Scharnagl, W. Renner, U. Seelhorst, B. Wellnitz, J. Kinkeldei, B. O. Boehm, G. Weihrauch, and W. Maerz
Independent Association of Low Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels With All-Cause and Cardiovascular Mortality
Arch Intern Med, June 23, 2008; 168(12): 1340 - 1349.
[Abstract] [Full Text] [PDF]

Home page
 BMJHome page
M. F Holick
Deficiency of sunlight and vitamin D
BMJ, June 14, 2008; 336(7657): 1318 - 1319.
[Full Text] [PDF]

Home page
 BMJHome page
J. L Sievenpiper, E. A McIntyre, M. Verrill, R. Quinton, and S. H S Pearce
Unrecognised severe vitamin D deficiency
BMJ, June 14, 2008; 336(7657): 1371 - 1374.
[Full Text] [PDF]

Home page
 JBJSHome page
L. Gehrig, J. Lane, and M. I. O'Connor
Osteoporosis: Management and Treatment Strategies for Orthopaedic Surgeons
J. Bone Joint Surg. Am., June 1, 2008; 90(6): 1362 - 1374.
[Full Text] [PDF]

Home page
 Arch Pediatr Adolesc MedHome page
C. M. Gordon, H. A. Feldman, L. Sinclair, A. L. Williams, P. K. Kleinman, J. Perez-Rossello, and J. E. Cox
Prevalence of Vitamin D Deficiency Among Healthy Infants and Toddlers
Arch Pediatr Adolesc Med, June 1, 2008; 162(6): 505 - 512.
[Abstract] [Full Text] [PDF]

Home page
 Arch Pediatr Adolesc MedHome page
A. J. Rovner and K. O. O'Brien
Hypovitaminosis D Among Healthy Children in the United States: A Review of the Current Evidence
Arch Pediatr Adolesc Med, June 1, 2008; 162(6): 513 - 519.
[Abstract] [Full Text] [PDF]

Home page
 Int J EpidemiolHome page
R. M Lucas, A. J McMichael, B. K Armstrong, and W. T Smith
Estimating the global disease burden due to ultraviolet radiation exposure
Int. J. Epidemiol., June 1, 2008; 37(3): 654 - 667.
[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
M. L. Melamed, P. Muntner, E. D. Michos, J. Uribarri, C. Weber, J. Sharma, and P. Raggi
Serum 25-Hydroxyvitamin D Levels and the Prevalence of Peripheral Arterial Disease: Results from NHANES 2001 to 2004
Arterioscler Thromb Vasc Biol, June 1, 2008; 28(6): 1179 - 1185.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
S. A. Bowden, R. F. Robinson, R. Carr, and J. D. Mahan
Prevalence of Vitamin D Deficiency and Insufficiency in Children With Osteopenia or Osteoporosis Referred to a Pediatric Metabolic Bone Clinic
Pediatrics, June 1, 2008; 121(6): e1585 - e1590.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
L. Rejnmark, P. Vestergaard, L. Heickendorff, and L. Mosekilde
Plasma 1,25(OH)2D levels decrease in postmenopausal women with hypovitaminosis D.
Eur. J. Endocrinol., April 1, 2008; 158(4): 571 - 576.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Chem.Home page
G. Beastall and S. Rainbow
Vitamin D Reinvented: Implications for Clinical Chemistry
Clin. Chem., April 1, 2008; 54(4): 630 - 632.
[Full Text] [PDF]

Home page
 FASEB J.Home page
J. C. McCann and B. N. Ames
Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction?
FASEB J, April 1, 2008; 22(4): 982 - 1001.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
S T Weiss and A A Litonjua
Author's reply
Thorax, March 1, 2008; 63(3): 293 - 293.
[Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
E. T Aasheim, D. Hofso, J. Hjelmesaeth, K. I Birkeland, and T. Bohmer
Vitamin status in morbidly obese patients: a cross-sectional study
Am. J. Clinical Nutrition, February 1, 2008; 87(2): 362 - 369.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
T. J. Wang, M. J. Pencina, S. L. Booth, P. F. Jacques, E. Ingelsson, K. Lanier, E. J. Benjamin, R. B. D'Agostino, M. Wolf, and R. S. Vasan
Vitamin D Deficiency and Risk of Cardiovascular Disease
Circulation, January 29, 2008; 117(4): 503 - 511.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
A. H. Lichtenstein, H. Rasmussen, W. W. Yu, S. R. Epstein, and R. M. Russell
Modified MyPyramid for Older Adults
J. Nutr., January 1, 2008; 138(1): 5 - 11.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
S. A Talwar, J. F Aloia, S. Pollack, and J. K Yeh
Dose response to vitamin D supplementation among postmenopausal African American women
Am. J. Clinical Nutrition, December 1, 2007; 86(6): 1657 - 1662.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
A. J Rovner, V. A Stallings, J. I Schall, M. B Leonard, and B. S Zemel
Vitamin D insufficiency in children, adolescents, and young adults with cystic fibrosis despite routine oral supplementation
Am. J. Clinical Nutrition, December 1, 2007; 86(6): 1694 - 1699.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
E. Hypponen, S. Turner, P. Cumberland, C. Power, and I. Gibb
Serum 25-Hydroxyvitamin D Measurement in a Large Population Survey with Statistical Harmonization of Assay Variation to an International Standard
J. Clin. Endocrinol. Metab., December 1, 2007; 92(12): 4615 - 4622.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
M. J. Rowling, C. Gliniak, J. Welsh, and J. C. Fleet
High Dietary Vitamin D Prevents Hypocalcemia and Osteomalacia in CYP27B1 Knockout Mice
J. Nutr., December 1, 2007; 137(12): 2608 - 2615.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
R. Bouillon, A. W. Norman, P. Lips, R. C. Cava, A. N. D. Javier, W. R. Howe, R. Dellavalle, G. I. Baroncelli, and M. F. Holick
Vitamin D Deficiency
N. Engl. J. Med., November 8, 2007; 357(19): 1980 - 1982.
[Full Text] [PDF]

Home page
 JNCI J Natl Cancer InstHome page
D. M. Freedman, A. C. Looker, S.-C. Chang, and B. I. Graubard
Prospective Study of Serum Vitamin D and Cancer Mortality in the United States
J Natl Cancer Inst, November 7, 2007; 99(21): 1594 - 1602.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
E. Giovannucci
Can Vitamin D Reduce Total Mortality?
Arch Intern Med, September 10, 2007; 167(16): 1709 - 1710.
[Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
S. M Kimball, M. R Ursell, P. O'Connor, and R. Vieth
Safety of vitamin D3 in adults with multiple sclerosis
Am. J. Clinical Nutrition, September 1, 2007; 86(3): 645 - 651.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by The American Society for Nutrition