| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
ORIGINAL RESEARCH COMMUNICATION |
1 From the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA (SKD, CHG, JKG, PJF, RAC, ST, MT, MAM, AHL, GED, and SBR); Tufts–New England Medical Center Hospital, Boston, MA (AGP and ES); the National Institute of Aging, National Institute of Health, Bethesda, MD (CD); the Duke Clinical Research Institute, Durham, NC (MVB); and the Pennington Biomedical Research Center, Baton Rouge, LA (JPD)
Background:There remains no consensus about the optimal dietary composition for sustained weight loss.
Objective:The objective was to examine the effects of 2 dietary macronutrient patterns with different glycemic loads on adherence to a prescribed regimen of calorie restriction (CR), weight and fat loss, and related variables.
Design:A randomized controlled trial (RCT) of diets with a high glycemic load (HG) or a low glycemic load (LG) at 30% CR was conducted in 34 healthy overweight adults with a mean (±SD) age of 35 ± 6 y and body mass index (kg/m2) of 27.6 ± 1.4. All food was provided for 6 mo in diets controlled for confounding variables, and subjects self-administered the plans for 6 additional months. Primary and secondary outcomes included energy intake measured by doubly labeled water, body weight and fatness, hunger, satiety, and resting metabolic rate.
Results:All groups consumed significantly less energy during CR than at baseline (P < 0.01), but changes in energy intake, body weight, body fat, and resting metabolic rate did not differ significantly between groups. Both groups ate more energy than provided (eg, 21% and 28% CR at 3 mo and 16% and 17% CR at 6 mo with HG and LG, respectively). Percentage weight change at 12 mo was –8.04 ± 4.1% in the HG group and –7.81 ± 5.0% in the LG group. There was no effect of dietary composition on changes in hunger, satiety, or satisfaction with the amount and type of provided food during CR.
Conclusions:These findings provide more detailed evidence to suggest that diets differing substantially in glycemic load induce comparable long-term weight loss.
Key Words: Glycemic load • caloric restriction • body weight • metabolism
This article has been cited by other articles:
|
|
 |
|
  K. A Varady, S. Bhutani, E. C Church, and M. C Klempel Short-term modified alternate-day fasting: a novel dietary strategy for weight loss and cardioprotection in obese adults Am. J. Clinical Nutrition, November 1, 2009; 90(5): 1138 - 1143. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. P. Solomon, J. M Haus, K. R Kelly, M. D Cook, M. Riccardi, M. Rocco, S. R Kashyap, H. Barkoukis, and J. P Kirwan Randomized trial on the effects of a 7-d low-glycemic diet and exercise intervention on insulin resistance in older obese humans Am. J. Clinical Nutrition, November 1, 2009; 90(5): 1222 - 1229. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Ahmed, S. K. Das, J. K. Golden, E. Saltzman, S. B. Roberts, and S. N. Meydani Calorie Restriction Enhances T-Cell-Mediated Immune Response in Adult Overweight Men and Women J Gerontol A Biol Sci Med Sci, November 1, 2009; 64A(11): 1107 - 1113. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. A. Aziz, L. S. Kenney, B. Goulet, and E.-S. Abdel-Aal Dietary Starch Type Affects Body Weight and Glycemic Control in Freely Fed but Not Energy-Restricted Obese Rats J. Nutr., October 1, 2009; 139(10): 1881 - 1889. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Del Corral, P. C. Chandler-Laney, K. Casazza, B. A. Gower, and G. R. Hunter Effect of Dietary Adherence with or without Exercise on Weight Loss: A Mechanistic Approach to a Global Problem J. Clin. Endocrinol. Metab., May 1, 2009; 94(5): 1602 - 1607. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. M. Sacks, G. A. Bray, V. J. Carey, S. R. Smith, D. H. Ryan, S. D. Anton, K. McManus, C. M. Champagne, L. M. Bishop, N. Laranjo, et al. Comparison of Weight-Loss Diets with Different Compositions of Fat, Protein, and Carbohydrates N. Engl. J. Med., February 26, 2009; 360(9): 859 - 873. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Shea, C. R French, J. Bishop, G. Martin, B. Roebothan, D. Pace, D. Fitzpatrick, and G. Sun Changes in the transcriptome of abdominal subcutaneous adipose tissue in response to short-term overfeeding in lean and obese men Am. J. Clinical Nutrition, January 1, 2009; 89(1): 407 - 415. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Maruyama, S. Sato, T. Ohira, K. Maeda, H. Noda, Y. Kubota, S. Nishimura, A. Kitamura, M. Kiyama, T. Okada, et al. The joint impact on being overweight of self reported behaviours of eating quickly and eating until full : cross sectional survey BMJ, October 21, 2008; 337(oct21_2): a2002 - a2002. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. E. Smith, K. L. Tucker, N. Yiannakouris, B. Garcia-Bailo, J. Mattei, C.-Q. Lai, L. D. Parnell, and J. M. Ordovas Perilipin Polymorphism Interacts with Dietary Carbohydrates to Modulate Anthropometric Traits in Hispanics of Caribbean Origin J. Nutr., October 1, 2008; 138(10): 1852 - 1858. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. L Deierlein, A. M. Siega-Riz, and A. Herring Dietary energy density but not glycemic load is associated with gestational weight gain Am. J. Clinical Nutrition, September 1, 2008; 88(3): 693 - 699. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Astrup Dietary Management of Obesity JPEN J Parenter Enteral Nutr, September 1, 2008; 32(5): 575 - 577. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. Ungvari, C. Parrado-Fernandez, A. Csiszar, and R. de Cabo Mechanisms Underlying Caloric Restriction and Lifespan Regulation: Implications for Vascular Aging Circ. Res., March 14, 2008; 102(5): 519 - 528. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-P. Chaput, A. Tremblay, E. B Rimm, C. Bouchard, and D. S Ludwig A novel interaction between dietary composition and insulin secretion: effects on weight gain in the Quebec Family Study Am. J. Clinical Nutrition, February 1, 2008; 87(2): 303 - 309. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Brand-Miller Effects of glycemic load on weight loss in overweight adults Am. J. Clinical Nutrition, October 1, 2007; 86(4): 1249 - 1250. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
