HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hlebowicz, J. Articles by Almér, L.-O. Search for Related Content PubMed PubMed Citation Articles by Hlebowicz, J. Articles by Almér, L.-O. Agricola Articles by Hlebowicz, J. Articles by Almér, L.-O.

Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects^1,2,3

¹ From the Departments of Medicine (JH, GD, and L-OA) and Radiology (OB), Malmö University Hospital, University of Lund, Lund, Sweden

Background: Previous studies of patients with type 2 diabetes showed that cinnamon lowers fasting serum glucose, triacylglycerol, and LDL- and total cholesterol concentrations.

Objective: We aimed to study the effect of cinnamon on the rate of gastric emptying, the postprandial blood glucose response, and satiety in healthy subjects.

Design: The gastric emptying rate (GER) was measured by using standardized real-time ultrasonography. Fourteen healthy subjects were assessed by using a crossover trial. The subjects were examined after an 8-h fast if they had normal fasting blood glucose concentrations. GER was calculated as the percentage change in the antral cross-sectional area 15–90 min after ingestion of 300 g rice pudding (GER1) or 300 g rice pudding and 6 g cinnamon (GER2).

Results: The median value of GER1 was 37%, and that of GER2 was 34.5%. The addition of cinnamon to the rice pudding significantly delayed gastric emptying and lowered the postprandial glucose response (P < 0.05 for both). The reduction in the postprandial blood glucose concentration was much more noticeable and pronounced than was the lowering of the GER. The effect of cinnamon on satiety was not significant.

Conclusions: The intake of 6 g cinnamon with rice pudding reduces postprandial blood glucose and delays gastric emptying without affecting satiety. Inclusion of cinnamon in the diet lowers the postprandial glucose response, a change that is at least partially explained by a delayed GER.

Key Words: Gastric emptying • blood glucose • healthy subjects • cinnamon • diabetes • satiety

This article has been cited by other articles:

				M. Tang, D E. Larson-Meyer, and M. Liebman Effect of cinnamon and turmeric on urinary oxalate excretion, plasma lipids, and plasma glucose in healthy subjects Am. J. Clinical Nutrition, May 1, 2008; 87(5): 1262 - 1267. [Abstract] [Full Text] [PDF]

				H. Cao, J. F. Urban Jr, and R. A. Anderson Cinnamon Polyphenol Extract Affects Immune Responses by Regulating Anti- and Proinflammatory and Glucose Transporter Gene Expression in Mouse Macrophages J. Nutr., May 1, 2008; 138(5): 833 - 840. [Abstract] [Full Text] [PDF]

				J. H. O'Keefe, N. M. Gheewala, and J. O. O'Keefe Dietary Strategies for Improving Post-Prandial Glucose, Lipids, Inflammation, and Cardiovascular Health J. Am. Coll. Cardiol., January 22, 2008; 51(3): 249 - 255. [Abstract] [Full Text] [PDF]