HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Moresco, J. J Articles by Yates, J. R PubMed PubMed Citation Articles by Moresco, J. J Articles by Yates, J. R, III Agricola Articles by Moresco, J. J Articles by Yates, J. R

Quantitative mass spectrometry as a tool for nutritional proteomics^1,2,3

¹ From the Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA (JJM and JRY), and the National Institute of Biological Sciences, Beijing, China (M-QD)

The goal of nutritional science is to determine the effect of dietary components. Proteomics has emerged as a method to study proteins on a large scale. The proteomic information gathered from a sample, whether a biological fluid, cell, or tissue, includes not only the identities of proteins present but also their quantities and posttranslational modifications. Recent advances in mass spectrometry make it possible to accurately measure concentrations of thousands of proteins derived from such complex biological samples. Quantitative data will provide increased understanding of the dynamic changes in the proteome induced by dietary components.