AJCN EB Program 2010 Early Registration
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Clin Nutr 89: 1059-1067, 2009. First published February 18, 2009; doi:10.3945/ajcn.2008.27182
 American Journal of Clinical Nutrition, doi:10.3945/ajcn.2008.27182
Vol. 89, No. 4, 1059-1067, April 2009
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
89/4/1059    most recent
ajcn.2008.27182v1
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Villegas, R.
Right arrow Articles by Shu, X. O.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Villegas, R.
Right arrow Articles by Shu, X. O.
Agricola
Right arrow Articles by Villegas, R.
Right arrow Articles by Shu, X. O.
© 2009 American Society for Clinical Nutrition

ORIGINAL RESEARCH COMMUNICATION

Dietary calcium and magnesium intakes and the risk of type 2 diabetes: the Shanghai Women's Health Study

Raquel Villegas1,2,3, Yu-Tang Gao1,2,3, Qi Dai1,2,3, Gong Yang1,2,3, Hui Cai1,2,3, Honglan Li1,2,3, Wei Zheng1,2,3 and Xiao Ou Shu1,2,3

1 From the Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, TN (RV, QD, GY, HC, WZ, and XOS), and the Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China (Y-TG and HL).

2 Supported by the National Cancer Institute (US Public Health Service grant R01 CA070867).

3 Reprints not available. Address correspondence to R Villegas, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, 2525 West End Avenue, Suite 600, Nashville, TN 37203-1738. E-mail: raquel.villegas{at}vanderbilt.edu.

Background: Diet plays a key role in the development of type 2 diabetes (T2D), but little is known about the contributions of specific nutrients in populations in which dietary patterns differ from Western populations.

Objective: We examined associations between calcium and magnesium intakes and the risk of T2D in a Chinese population.

Design: We used data from a population-based, prospective study of 64,191 women who were free of T2D or other chronic diseases at study recruitment and were living in urban Shanghai, China. Dietary intake, physical activity, and anthropometric measurements were assessed through in-person interviews. A Cox regression model was used to evaluate the association of the exposures under study with the risk of T2D.

Results: An inverse association between calcium and magnesium intakes and T2D risk was observed. The relative risks for the lowest to the highest quintiles of calcium intake were 1.00, 0.82, 0.73, 0.67, and 0.74 (P for trend < 0.001), and for magnesium they were 1.00, 0.84, 0.84, 0.79, and 0.86 (P for trend < 0.001). Milk intake was also inversely associated with the risk of T2D.

Conclusion: Our data suggest that calcium and magnesium intakes may protect against the development of T2D in this population.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2009 by The American Society for Nutrition