AJCN North Carolina Research Campus
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by STANBURY, J. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by STANBURY, J. B.
Agricola
Right arrow Articles by STANBURY, J. B.

American Journal of Clinical Nutrition, Vol 9, 669-675, Copyright © 1961 by The American Society for Clinical Nutrition, Inc.

The Metabolic Basis for Certain Disorders of the Thyroid Gland

JOHN B. STANBURY M.D.1

1 From the Departments of Medicine, Harvard Medical School and Massachusetts General Hospital (Thyroid Unit), Boston, Massachusetts

At least five metabolically distinct disorders of the thyroid gland are now recognized which impair the function of the gland and lead to hypothyroidism and goiter.

The patients which have been described in each group are probably homozygous for a recessive gene which controls the synthesis of an enzyme necessary for a specific step in thyroidal hormonogenesis.

Relatives of these patients often have goiter but are otherwise normal. They are presumed to be heterozygous for the defect for which the probands are homozygous.

The quantity of iodine in the diet in some cases determines the impact of the genetically determined defect on the patient.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1961 by The American Society for Nutrition