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American Journal of Clinical Nutrition, Vol 9, 705-707, Copyright © 1961 by The American Society for Clinical Nutrition, Inc.

Effect of Food on the Absorption of Vitamin B12

SHELDON SIEGEL M.S.1, BACON F. CHOW PH.D.1, KUNIO OKUDA M.D.1, SUE CHEN M.S.1, and EDWARD J. HANUS M.S.1

1 From The Johns Hopkins University, School of Hygiene & Public Health, Department of Biochemistry, Baltimore, Maryland, and Merck & Co., Inc., Product Development, Rahway, New Jersey

Data involving the measurement of absorbed radioactivity following the oral administration of labeled vitamin B12 are presented which show greater apparent absorption of the vitamin in prefed human subjects or rats, using as a criteria urinary excretion in man and organ (liver and kidneys) uptake or excretion in rats.






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Copyright © 1961 by The American Society for Nutrition