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Letter to the Editor |
Purdue University Department of Foods and Nutrition 1264 Stone Hall West Lafayette, IN 47907-1264
Dear Sir:
In a recent review article that examined the evidence of a link between dairy foods and bone health, Weinsier and Krumdieck (1) conclude that "the body of scientific evidence appears inadequate to support a recommendation for daily intake of dairy foods to promote bone health in the general US population." They base their conclusions on a division of studies into those that showed a favorable effect of dairy food intake on bone health and those that did not. They prioritized studies according to the strength of the evidence. Category A studies (the strongest) were randomized controlled trials or longitudinal cohorts with
3000 participants who were followed for >5 y. However, these 2 types of studies are not equivalent. Observational studies can accurately assess the outcome measures of bone mineral density or fracture, but their ability to assess dietary intakes is weak. Large size does not overcome that weakness; it merely adds a spurious sense of accuracy. The number of epidemiologic studies that did not show a significant relation is not surprising considering the weak ability to determine the independent variable.
Observational studies of the effect of folate on neural tube defects showed a pattern nearly identical to that found for calcium. It was the randomized controlled trials that confirmed the importance of increasing folate intake during the reproductive years.
If only randomized controlled trials were assigned to category A, then studies showing a favorable relation between dairy food intake and bone health would number 5 and span age groups ranging from 11 y through menopause. Studies showing an unfavorable effect of dairy food intake on bone health would have no category A studies.
Thus, using the same evidence as that used by the authors, we conclude that adequate dairy consumption is supportive of good bone health. One of us recently reviewed this same literature and came to just that conclusion (2).
REFERENCES
This article has been cited by other articles:
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L. D McCabe, B. R Martin, G. P McCabe, C. C Johnston, C. M Weaver, and M. Peacock Dairy intakes affect bone density in the elderly Am. J. Clinical Nutrition, October 1, 2004; 80(4): 1066 - 1074. [Abstract] [Full Text] [PDF] |
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