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FIGURE 1. Images of brain responses in the 22 women and the 22 men to hunger and satiation at +8 (hunger) and -4 mm (satiation) from a horizontal plane between the anterior and posterior commissures (coordinates of the Talairach and Tournoux brain atlas; 23). The images on the right are overlaps of the images for the women and the men. The right hemisphere in each section is on the readers right. Brain areas with a significant increase in regional cerebral blood flow in response to hunger or satiation are shown in blue for the women and in yellow for the men. Bold colors represent the statistical level of P < 0.005, and transparent colors represent the level of 0.005 P < 0.05. Brain areas with a significant increase in regional cerebral blood flow in response to hunger or satiation in both sexes are shown in red. Images were generated with the use of positron emission tomography and magnetic resonance imaging data. Color-coded images were superimposed on an average of the subjects brain magnetic resonance images (gray-scale image). The figure is intended only for visual inspection of some regions of the brain, including the putamen (PU), insula (INS), caudate nucleus (CN), frontal operculum (FROP), thalamus (TH), superior temporal gyrus (STG), middle temporal gyrus (MTG), ventrolateral prefrontal cortex (VLPFC), and inferior occipital gyrus (IOG). Sex differences in brain responses to hunger and satiation and their relative significance were assessed by statistical parametric mapping and are shown in Tables 2 and 3.
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