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American Journal of Clinical Nutrition, Vol 68, 1157-1173, Copyright © 1998 by The American Society for Clinical Nutrition, Inc


REVIEW ARTICLES

Dietary fat intake does affect obesity!

GA Bray and BM Popkin
Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, USA.

There is a difference of opinion about whether the percentage of dietary fat plays an important role in the rising prevalence of overweight and in its treatment once it has developed. We believe that ample research from animal and clinical studies, from controlled trials, and from epidemiologic and ecologic analyses provides strong evidence that dietary fat plays a role in the development and treatment of obesity. A reduction in fat intake reduces the gap between total energy intake and total energy expenditure and thus is an effective strategy for reducing the present epidemic of obesity worldwide. A review of the results from 28 clinical trials that studied the effects of a reduction in the amount of energy from fat in the diet showed that a reduction of 10% in the proportion of energy from fat was associated with a reduction in weight of 16 g/d. We thus conclude that dietary fat plays a role in the development of obesity. To reduce the prevalence of obesity, there must be an increase in energy expenditure, a reduction in total energy intake, or both. This goal can be facilitated by reducing the amount of fat in the diet.


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Home page
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Home page
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Home page
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Home page
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Home page
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[Abstract] [Full Text] [PDF]


Home page
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[Full Text] [PDF]


Home page
ANN INTERN MEDHome page
W. C. Willett
Reduced-Carbohydrate Diets: No Roll in Weight Management?
Ann Intern Med, May 18, 2004; 140(10): 836 - 837.
[Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
L. S Gross, L. Li, E. S Ford, and S. Liu
Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment
Am. J. Clinical Nutrition, May 1, 2004; 79(5): 774 - 779.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
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Am. J. Clinical Nutrition, April 1, 2004; 79(4): 537 - 543.
[Abstract] [Full Text] [PDF]


Home page
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Arch Intern Med, January 26, 2004; 164(2): 210 - 217.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
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[Abstract] [Full Text] [PDF]


Home page
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Recent Prog. Horm. Res., January 1, 2004; 59(1): 267 - 285.
[Abstract] [Full Text]


Home page
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Interaction between a peroxisome proliferator-activated receptor {gamma} gene polymorphism and dietary fat intake in relation to body mass
Hum. Mol. Genet., November 15, 2003; 12(22): 2923 - 2929.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
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Am. J. Clinical Nutrition, November 1, 2003; 78(5): 920 - 927.
[Abstract] [Full Text] [PDF]


Home page
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Experimental Biology and Medicine, November 1, 2003; 228(10): 1181 - 1189.
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Home page
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Home page
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Home page
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Home page
Am. J. Clin. Nutr.Home page
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Am. J. Clinical Nutrition, September 1, 2003; 78(3): 617S - 625.
[Abstract] [Full Text] [PDF]


Home page
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Arch Pediatr Adolesc Med, August 1, 2003; 157(8): 773 - 779.
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Home page
Am. J. Clin. Nutr.Home page
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Relative influence of diet and physical activity on body composition in urban Chinese adults
Am. J. Clinical Nutrition, June 1, 2003; 77(6): 1409 - 1416.
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Home page
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Am. J. Clinical Nutrition, June 1, 2003; 77(6): 1417 - 1425.
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Home page
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Home page
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[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
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